Weir Lab
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Selected Publications
* denotes shared first authorship
✉
denotes shared corresponding authorship
"Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates"
Altmannova V*, Firlej M*, Müller F, Janning P, Rauleder R, Rousova D, Schäffler A, Bange T, Weir JR. Nucleic Acids Research, March 2023
"Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin"
Kabackci Z, Reicle HE, Lemke B, Rousova D, Gupta S, Weber J, Schleiiffer A, Weir JR
✉
, Lehner CF
✉
. PLoS Genetics, December 2022
"Unwinding during stressful times: Mechanisms of helicases in meiotic recombination"
Firlej F & Weir JR, Current Topics in Developmental Biology. July 2022
"Studying meiosis in mitosis: Activating the meiosis-specific Red1-Hop1-Mek1 complex in mitotic budding yeast cells"
Nivsarkar V, Chen L, Funk SK, Weir JR, Vader G. bioR
χ
iv April 2022
"Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation"
Rousova D, Nivsarkar V*, Altmannova V*, Raina VB*, Funk SK, Liedtke D, Janning P, Müller F, Reichle H, Vader G, Weir JR
.
eLife December 2021
"InteBac - An integrated bacterial and baculovirus expression vector suite"
Altmannova V, Blaha A, Astrinidis S, Reichle H, Weir JR. Protein Science September 2020
"Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly"
Villar-Fernández MA, Cardoso da Silva R, Firlej M, Pan D, Weir E, Sarembe A, Raina VB, Bange T, Weir JR, Vader G. Life Science Alliance August 2020
"Insights from biochemical reconstitution into the architecture of human kinetochores"
Weir JR*✉, Faesen AC*, Klare K*
et al
. Nature September 2016
"Progress in the structural and functional characterization of kinetochores"
Pesenti M, Weir JR, Musacchio A. Current Opinion in Structural Biology April 2016
"CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores"
Klare K*, Weir JR*,
et al
. JCB July 2015
"The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities"
Falk S*, Weir JR*,
et al.
, Molecular Cell September 2014
"The pseudo GTPase CENP-M drives human kinetochore assembly"
Basilico F*, Maffini S*, Weir JR*,
et al.
, eLife July 2014
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